Quiescent and Proliferative Fibroblasts Exhibit Differential p300 HAT Activation through Control of 5-Methoxytryptophan Production

Quiescent fibroblasts possess unique genetic program and exhibit high metabolic activity distinct from proliferative fibroblasts. In response to inflammatory stimulation, quiescent fibroblasts are more active in expressing cyclooxygenase-2 and other proinflammatory genes than proliferative fibroblas...

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Bibliographic Details
Main Authors: Cheng, Huei-Hsuan, Wang, Kai-Hsuan, Chu, Ling-yun, Chang, Tzu-Ching, Kuo, Cheng-Chin, Wu, Kenneth K.
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3921189/