Genes Associated with SLE Are Targets of Recent Positive Selection

Genes Associated with SLE Are Targets of Recent Positive Selection

The reasons for the ethnic disparities in the prevalence of systemic lupus erythematosus (SLE) and the relative high frequency of SLE risk alleles in the population are not fully understood. Population genetic factors such as natural selection alter allele frequencies over generations and may help...

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Bibliographic Details
Main Authors: Ramos, Paula S., Shaftman, Stephanie R., Ward, Ralph C., Langefeld, Carl D.
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3920976/

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