Genes Associated with SLE Are Targets of Recent Positive Selection
The reasons for the ethnic disparities in the prevalence of systemic lupus erythematosus (SLE) and the relative high frequency of SLE risk alleles in the population are not fully understood. Population genetic factors such as natural selection alter allele frequencies over generations and may help...
Main Authors: | , , , |
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Format: | Online |
Language: | English |
Published: |
Hindawi Publishing Corporation
2014
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3920976/ |