GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region

In a Genome Wide Association Study (GWAS) of individuals of European ancestry afflicted with Systemic Lupus Erythematosus (SLE) the extensive utilization of imputation, stepwise multiple regression, lasso regularization, and increasing study power by utilizing False Discovery Rate (FDR) instead of a...

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Bibliographic Details
Main Authors: Armstrong, Don L., Zidovetzki, Raphael, Alarcón-Riquelme, Marta E, Tsao, Betty P, Criswell, Lindsey A, Kimberly, Robert P, Harley, John B, Sivils, Kathy L, Vyse, Timothy J, Gaffney, Patrick M., Langefeld, Carl D, Jacob, Chaim O.
Format: Online
Language:English
Published: 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4156543/