Tregitope Peptides: The Active Pharmaceutical Ingredient of IVIG?

Five years ago, we reported the identification and characterization of several regulatory T-cell epitopes (now called Tregitopes) that were discovered in the heavy and light chains of IgG (De Groot et al. Blood, 2008). When added ex vivo to human PBMCs, these Tregitopes activated regulatory T cells...

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Bibliographic Details
Main Authors: De Groot, Anne S., Cousens, Leslie, Mingozzi, Federico, Martin, William
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3886585/