Potential Application of Tregitopes as Immunomodulating Agents in Multiple Sclerosis
The induction of immunologic tolerance is an important clinical goal in autoimmunity. CD4+ regulatory T (Treg) cells, defined by the expression of the transcription factor forkhead box P3 (FoxP3), play a central role in the control of autoimmune responses. Quantitative and qualitative defects of Tre...
Main Authors: | , , , |
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Format: | Online |
Language: | English |
Published: |
Hindawi Publishing Corporation
2011
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3175387/ |