The dynamics of genome replication using deep sequencing

The dynamics of genome replication using deep sequencing

Eukaryotic genomes are replicated from multiple DNA replication origins. We present complementary deep sequencing approaches to measure origin location and activity in Saccharomyces cerevisiae. Measuring the increase in DNA copy number during a synchronous S-phase allowed the precise determination o...

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Bibliographic Details
Main Authors: Müller, Carolin A., Hawkins, Michelle, Retkute, Renata, Malla, Sunir, Wilson, Ray, Blythe, Martin J., Nakato, Ryuichiro, Komata, Makiko, Shirahige, Katsuhiko, de Moura, Alessandro P.S., Nieduszynski, Conrad A.
Format: Online
Language:English
Published: Oxford University Press 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3874191/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3874191/

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