Accelerated growth in the absence of DNA replication origins

DNA replication initiates at defined sites called origins, which serve as binding sites for initiator proteins that recruit the replicative machinery. Origins differ in number and structure across the three domains of life1 and their properties determine the dynamics of chromosome replication. Bacte...

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Bibliographic Details
Main Authors: Hawkins, Michelle, Malla, Sunir, Blythe, Martin J., Nieduszynski, Conrad A., Allers, Thorsten
Format: Online
Language:English
Published: 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3843117/