High-resolution replication profiles define the stochastic nature of genome replication initiation and termination
Eukaryotic genome replication is stochastic, and each cell uses a different cohort of replication origins. We demonstrate that interpreting high-resolution Saccharomyces cerevisiae genome replication data with a mathematical model allows quantification of the stochastic nature of genome replication,...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2013
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| Online Access: | http://eprints.nottingham.ac.uk/2525/ http://eprints.nottingham.ac.uk/2525/ http://eprints.nottingham.ac.uk/2525/ http://eprints.nottingham.ac.uk/2525/2/Conrad_Nieduszynski--High-Resolution.pdf |