Cathepsin E Deficiency Impairs Autophagic Proteolysis in Macrophages
Cathepsin E is an endosomal aspartic proteinase that is predominantly expressed in immune-related cells. Recently, we showed that macrophages derived from cathepsin E-deficient (CatE −/−) mice display accumulation of lysosomal membrane proteins and abnormal membrane trafficking. In this study, we de...
| Main Authors: | , , , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Public Library of Science
2013
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3855462/ |