Differential Regulation of Cathepsin S and Cathepsin L in Interferon γ–treated Macrophages

Cathepsin S (catS) and cathepsin L (catL) mediate late stages of invariant chain (Ii) degradation in discrete antigen-presenting cell types. Macrophages (Mφs) are unique in that they express both proteases and here we sought to determine the relative contribution of each enzyme. We observe that catL...

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Bibliographic Details
Main Authors: Beers, Courtney, Honey, Karen, Fink, Susan, Forbush, Katherine, Rudensky, Alexander
Format: Online
Language:English
Published: The Rockefeller University Press 2003
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193812/