Functional Haplotypes in the Promoter Region of Transcription Factor Nrf2 in Chronic Obstructive Pulmonary Disease

Nuclear factor (erythroid-derived 2)-like 2 (Nrf2) protects against oxidative stress which is important in the pathogenesis of chronic obstructive pulmonary disease (COPD). Three single nucleotide polymorphisms and 1 triplet repeat polymorphism are found in the promoter region of the Nrf2 gene. Mole...

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Bibliographic Details
Main Authors: Hua, Chung-Ching, Chang, Liang-Che, Tseng, Jo-Chi, Chu, Chien-Ming, Liu, Yu-Chih, Shieh, Wen-Bin
Format: Online
Language:English
Published: IOS Press 2010
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3833611/