The Ratio of Hmox1/Nrf2 mRNA Level in the Tumor Tissue Is a Predictor of Distant Metastasis in Colorectal Cancer

The Ratio of Hmox1/Nrf2 mRNA Level in the Tumor Tissue Is a Predictor of Distant Metastasis in Colorectal Cancer

Heme oxygenase 1 (Hmox1) plays an important role in the growth and spread of tumor, and its expression is regulated positively by Nrf2 [nuclear factor (erythroid-derived 2)-like 2; NFE2L2] and negatively by kelch-like ECH-associated protein 1 (Keap1) and by BTB and CNC homology 1 (Bach1). Both Hmox1...

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Bibliographic Details
Main Authors: Chang, Liang-Che, Fan, Chung-Wei, Tseng, Wen-Ko, Chein, Hui-Ping, Hsieh, Tsan-Yu, Chen, Jim-Ray, Hwang, Cheng-Cheng, Hua, Chung-Ching
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5141536/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5141536/

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