Liquid chromatographic–mass spectrometric method for simultaneous determination of small organic acids potentially contributing to acidosis in severe malaria☆
•Acidosis is an important contributor to mortality in patients with severe malaria.•A novel LC–MS method for simultaneous determination of 8 potential small organic acids contributing to acidosis.•Anion exchange SPE coupled with HILIC and ion trap LC–MS was utilized for separation and detection.•Thi...
| Main Authors: | , , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Elsevier
2013
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827507/ |