Reversed-phase liquid-chromatographic mass spectrometric N-glycan analysis of biopharmaceuticals

N-Glycosylation is a common post-translational modification of monoclonal antibodies with a potential effect on the efficacy and safety of the drugs; detailed knowledge about this glycosylation is therefore crucial. We have developed a reversed-phase liquid chromatographic–mass spectrometric method,...

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Bibliographic Details
Main Authors: Higel, Fabian, Demelbauer, Uwe, Seidl, Andreas, Friess, Wolfgang, Sörgel, Fritz
Format: Online
Language:English
Published: Springer-Verlag 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3581771/