Proton-Sensing Ovarian Cancer G Protein-Coupled Receptor 1 on Dendritic Cells Is Required for Airway Responses in a Murine Asthma Model

Proton-Sensing Ovarian Cancer G Protein-Coupled Receptor 1 on Dendritic Cells Is Required for Airway Responses in a Murine Asthma Model

Ovarian cancer G protein-coupled receptor 1 (OGR1) stimulation by extracellular protons causes the activation of G proteins and subsequent cellular functions. However, the physiological and pathophysiological roles of OGR1 in airway responses remain largely unknown. In the present study, we show tha...

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Bibliographic Details
Main Authors: Aoki, Haruka, Mogi, Chihiro, Hisada, Takeshi, Nakakura, Takashi, Kamide, Yosuke, Ichimonji, Isao, Tomura, Hideaki, Tobo, Masayuki, Sato, Koichi, Tsurumaki, Hiroaki, Dobashi, Kunio, Mori, Tetsuya, Harada, Akihiro, Yamada, Masanobu, Mori, Masatomo, Ishizuka, Tamotsu, Okajima, Fumikazu
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823589/

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