Heterologous vaccination against human tuberculosis modulates antigen-specific CD4+ T-cell function

Heterologous vaccination against human tuberculosis modulates antigen-specific CD4+ T-cell function

Heterologous prime-boost strategies hold promise for vaccination against tuberculosis. However, the T-cell characteristics required for protection are not known. We proposed that boost vaccines should induce long-lived functional and phenotypic changes to T cells primed by Bacille Calmette Guerin (B...

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Bibliographic Details
Main Authors: Dintwe, One B, Day, Cheryl L, Smit, Erica, Nemes, Elisa, Gray, Clive, Tameris, Michele, McShane, Helen, Mahomed, Hassan, Hanekom, Willem A, Scriba, Thomas J
Format: Online
Language:English
Published: Wiley-VCH Verlag GmbH & Co 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3816254/

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