Single nucleotide polymorphisms in toll-like receptor 6 are associated with altered lipopeptide- and mycobacteria-induced IL-6 secretion

Single nucleotide polymorphisms in toll-like receptor 6 are associated with altered lipopeptide- and mycobacteria-induced IL-6 secretion

Toll-like receptors (TLRs) are critical mediators of the immune response to pathogens. The influence of human TLR6 polymorphisms on susceptibility to infection is only partially understood. Most microbes contain lipopeptides recognized by TLR2/1 or TLR2/6 heterodimers. Our aim was to determine wheth...

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Bibliographic Details
Main Authors: Shehu Shey, Muki, Randhawa, April Kaur, Bowmaker, Mark, Smith, Elizabeth, Jens Scriba, Thomas, de Kock, Marwou, Mahomed, Hassan, Hussey, Gregory, Richard Hawn, Thomas, Albert Hanekom, Willem
Format: Online
Language:English
Published: 2010
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3518443/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3518443/

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