NLRP3 Inflammasome and Host Protection against Bacterial Infection

The inflammasome is a multi-protein complex that induces maturation of inflammatory cytokines interleukin (IL)-1β and IL-18 through activation of caspase-1. Several nucleotide binding oligomerization domain-like receptor family members, including NLRP3, recognize unique microbial and danger componen...

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Bibliographic Details
Main Authors: Kim, Jwa-Jin, Jo, Eun-Kyeong
Format: Online
Language:English
Published: The Korean Academy of Medical Sciences 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3792593/