Targeting BIG3–PHB2 interaction to overcome tamoxifen resistance in breast cancer cells

Targeting BIG3–PHB2 interaction to overcome tamoxifen resistance in breast cancer cells

The acquisition of endocrine resistance is a common obstacle in endocrine therapy of patients with oestrogen receptor-α (ERα)-positive breast tumours. We previously demonstrated that the BIG3–PHB2 complex has a crucial role in the modulation of oestrogen/ERα signalling in breast cancer cells. Here w...

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Bibliographic Details
Main Authors: Yoshimaru, Tetsuro, Komatsu, Masato, Matsuo, Taisuke, Chen, Yi-An, Murakami, Yoichi, Mizuguchi, Kenji, Mizohata, Eiichi, Inoue, Tsuyoshi, Akiyama, Miki, Yamaguchi, Rui, Imoto, Seiya, Miyano, Satoru, Miyoshi, Yasuo, Sasa, Mitsunori, Nakamura, Yusuke, Katagiri, Toyomasa
Format: Online
Language:English
Published: Nature Pub. Group 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3791465/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3791465/

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