Comparing Zinc Finger Nucleases and Transcription Activator-Like Effector Nucleases for Gene Targeting in Drosophila

Comparing Zinc Finger Nucleases and Transcription Activator-Like Effector Nucleases for Gene Targeting in Drosophila

Zinc-finger nucleases have proven to be successful as reagents for targeted genome manipulation in Drosophila melanogaster and many other organisms. Their utility has been limited, however, by the significant failure rate of new designs, reflecting the complexity of DNA recognition by zinc fingers....

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Bibliographic Details
Main Authors: Beumer, Kelly J., Trautman, Jonathan K., Christian, Michelle, Dahlem, Timothy J., Lake, Cathleen M., Hawley, R. Scott, Grunwald, David J., Voytas, Daniel F., Carroll, Dana
Format: Online
Language:English
Published: Genetics Society of America 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789796/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789796/

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