Notch2-dependent classical dendritic cells orchestrate intestinal immunity against attaching and effacing bacterial pathogens

Notch2-dependent classical dendritic cells orchestrate intestinal immunity against attaching and effacing bacterial pathogens

Defense against attaching and effacing (A/E) bacteria requires the sequential generation of interleukin 23 (IL-23) and IL-22 to induce protective mucosal responses. While CD4+ and NKp46+ innate lymphoid cells (ILCs) are the critical source of IL-22 during infection, the precise source of IL-23 is un...

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Bibliographic Details
Main Authors: Satpathy, Ansuman T., Briseño, Carlos G., Lee, Jacob S., Ng, Dennis, Manieri, Nicholas A., KC, Wumesh, Wu, Xiaodi, Thomas, Stephanie R., Lee, Wan-Ling, Turkoz, Mustafa, McDonald, Keely G., Meredith, Matthew M., Song, Christina, Guidos, Cynthia J., Newberry, Rodney D., Ouyang, Wenjun, Murphy, Theresa L., Stappenbeck, Thaddeus S., Gommerman, Jennifer L., Nussenzweig, Michel C., Colonna, Marco, Kopan, Raphael, Murphy, Kenneth M.
Format: Online
Language:English
Published: 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3788683/

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