Hsp60 Chaperonin Acts as Barrier to Pharmacologically Induced Oxidative Stress Mediated Apoptosis in Tumor Cells with Differential Stress Response
Mitochondrial functions play a central role in energy metabolism and provide survival fitness to both normal and tumor cells. Mitochondrial chaperonin Hsp60 is involved in both pro- and anti-apoptotic functions, but how Hsp60 senses the mitochondria selective oxidative stress response is unknown. In...
Main Authors: | , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
Libertas Academica
2013
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3767580/ |