17AAG Treatment Accelerates Doxorubicin Induced Cellular Senescence: Hsp90 Interferes with Enforced Senescence of Tumor Cells
Hsp90 chaperone has been identified as an attractive pharmacological target to combat cancer. However, some metastatic tumors either fail to respond to Hsp90 inhibition or show recovery necessitating irreversible therapeutic strategies. In response to this enforced senescence has been proposed as an...
Main Authors: | , , , , |
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Format: | Online |
Language: | English |
Published: |
Libertas Academica
2012
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3422084/ |