Repercussion of Mitochondria Deformity Induced by Anti-Hsp90 Drug 17AAG in Human Tumor Cells

Repercussion of Mitochondria Deformity Induced by Anti-Hsp90 Drug 17AAG in Human Tumor Cells

Inhibiting Hsp90 chaperone roles using 17AAG induces cytostasis or apoptosis in tumor cells through destabilization of several mutated cancer promoting proteins. Although mitochondria are central in deciding the fate of cells, 17AAG induced effects on tumor cell mitochondria were largely unknown. He...

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Bibliographic Details
Main Authors: Vishal, Chaturvedi, Kumar, Jonnala Ujwal, Veera Brahmendra Swamy, Cherukuvada, Nandini, Rangaraj, Srinivas, Gunda, Kumaresan, Rathinam, Shashi, Singh, Sreedhar, Amere Subbarao
Format: Online
Language:English
Published: Libertas Academica 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3178438/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3178438/

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