TRP-ML1 functions as a lysosomal NAADP-sensitive Ca2+ release channel in coronary arterial myocytes

Nicotinic acid adenine dinucleotide phosphate (NAADP) is a potent intracellular Ca2+ signalling second messenger, but the mechanism of NAADP-induced Ca2+ release is still poorly understood. The present study tested the hypothesis that NAADP induces Ca2+ release from the lysosomal store via a TRP-ML1...

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Bibliographic Details
Main Authors: Zhang, Fan, Jin, Si, Yi, Fan, Li, Pin-Lan
Format: Online
Language:English
Published: John Wiley & Sons, Ltd 2009
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3752374/