The two-pore channel TPCN2 mediates NAADP-dependent Ca2+-release from lysosomal stores

The two-pore channel TPCN2 mediates NAADP-dependent Ca2+-release from lysosomal stores

Second messenger-induced Ca2+-release from intracellular stores plays a key role in a multitude of physiological processes. In addition to 1,4,5-inositol trisphosphate (IP3), Ca2+, and cyclic ADP ribose (cADPR) that trigger Ca2+-release from the endoplasmatic reticulum (ER), nicotinic acid adenine d...

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Bibliographic Details
Main Authors: Zong, Xiangang, Schieder, Michael, Cuny, Hartmut, Fenske, Stefanie, Gruner, Christian, Rötzer, Katrin, Griesbeck, Oliver, Harz, Hartmann, Biel, Martin, Wahl-Schott, Christian
Format: Online
Language:English
Published: Springer-Verlag 2009
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2719734/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2719734/

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