Allelic exclusion of the immunoglobulin heavy chain locus is independent of its nuclear localization in mature B cells

Allelic exclusion of the immunoglobulin heavy chain locus is independent of its nuclear localization in mature B cells

In developing B cells, the immunoglobulin heavy chain (IgH) locus is thought to move from repressive to permissive chromatin compartments to facilitate its scheduled rearrangement. In mature B cells, maintenance of allelic exclusion has been proposed to involve recruitment of the non-productive IgH...

Full description

Bibliographic Details
Main Authors: Holwerda, Sjoerd J. B., van de Werken, Harmen J. G., Ribeiro de Almeida, Claudia, Bergen, Ingrid M., de Bruijn, Marjolein J. W., Verstegen, Marjon J. A. M., Simonis, Marieke, Splinter, Erik, Wijchers, Patrick J., Hendriks, Rudi W., de Laat, Wouter
Format: Online
Language:English
Published: Oxford University Press 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3737562/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3737562/

Similar Items