Maintenance of Long-Range DNA Interactions after Inhibition of Ongoing RNA Polymerase II Transcription

A relationship exists between nuclear architecture and gene activity and it has been proposed that the activity of ongoing RNA polymerase II transcription determines genome organization in the mammalian cell nucleus. Recently developed 3C and 4C technology allowed us to test the importance of transc...

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Bibliographic Details
Main Authors: Palstra, Robert-Jan, Simonis, Marieke, Klous, Petra, Brasset, Emilie, Eijkelkamp, Bart, de Laat, Wouter
Format: Online
Language:English
Published: Public Library of Science 2008
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2243019/