Sonic Hedgehog Promotes Tumor Cell Survival by Inhibiting CDON Pro-Apoptotic Activity
CDON is a novel Sonic Hedgehog (SHH) dependence receptor and targeting the SHH-CDON interaction could represent an alternative therapeutic strategy for patients suffering from tumors that express high SHH levels.
Main Authors: | Delloye-Bourgeois, Céline, Gibert, Benjamin, Rama, Nicolas, Delcros, Jean-Guy, Gadot, Nicolas, Scoazec, Jean-Yves, Krauss, Robert, Bernet, Agnès, Mehlen, Patrick |
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Format: | Online |
Language: | English |
Published: |
Public Library of Science
2013
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3735457/ |
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