Cooperativity and Rapid Evolution of Cobound Transcription Factors in Closely Related Mammals

To mechanistically characterize the microevolutionary processes active in altering transcription factor (TF) binding among closely related mammals, we compared the genome-wide binding of three tissue-specific TFs that control liver gene expression in six rodents. Despite an overall fast turnover of...

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Bibliographic Details
Main Authors: Stefflova, Klara, Thybert, David, Wilson, Michael D., Streeter, Ian, Aleksic, Jelena, Karagianni, Panagiota, Brazma, Alvis, Adams, David J., Talianidis, Iannis, Marioni, John C., Flicek, Paul, Odom, Duncan T.
Format: Online
Language:English
Published: Cell Press 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3732390/