BRCA1 deficiency results in impaired Nrf2-mediated antioxidant responses followed by cell death, with estradiol rescuing the effect by inducing Nrf2 stabilization.
Bibliographic Details
| Main Authors: |
Gorrini, Chiara,
Baniasadi, Pegah S.,
Harris, Isaac S.,
Silvester, Jennifer,
Inoue, Satoshi,
Snow, Bryan,
Joshi, Purna A.,
Wakeham, Andrew,
Molyneux, Sam D.,
Martin, Bernard,
Bouwman, Peter,
Cescon, David W.,
Elia, Andrew J.,
Winterton-Perks, Zoe,
Cruickshank, Jennifer,
Brenner, Dirk,
Tseng, Alan,
Musgrave, Melinda,
Berman, Hal K.,
Khokha, Rama,
Jonkers, Jos,
Mak, Tak W.,
Gauthier, Mona L. |
|---|
| Format: | Online
|
|---|
| Language: | English |
|---|
| Published: |
The Rockefeller University Press
2013
|
|---|
| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3727320/
|
|---|