Immune recognition of HLA molecules downmodulates CD8 expression on cytotoxic T lymphocytes
An HLA-A2+ cytotoxic T lymphocyte (CTL) line restricted by HLA-A2 in recognition of an influenza B virus nucleoprotein (BNP) peptide uses the CD8 coreceptor in the recognition of this viral peptide. Incubation of these CTL with BNP peptide in the absence of antigen-presenting cells downmodulates CD8...
| Format: | Online |
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| Language: | English |
| Published: |
The Rockefeller University Press
1991
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118759/ |