High Frequencies of Naive Melan-a/Mart-1–Specific Cd8+ T Cells in a Large Proportion of Human Histocompatibility Leukocyte Antigen (Hla)-A2 Individuals

High Frequencies of Naive Melan-a/Mart-1–Specific Cd8+ T Cells in a Large Proportion of Human Histocompatibility Leukocyte Antigen (Hla)-A2 Individuals

Using fluorescent HLA-A*0201 tetramers containing the immunodominant Melan-A/MART-1 (Melan-A) tumor-associated antigen (Ag), we previously observed that metastatic lymph nodes of melanoma patients contain high numbers of Ag-experienced Melan-A–specific cytolytic T lymphocytes (CTLs). In this paper,...

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Bibliographic Details
Main Authors: Pittet, Mikaël J., Valmori, Danila, Dunbar, P. Rod, Speiser, Daniel E., Liénard, Danielle, Lejeune, Ferdy, Fleischhauer, Katharina, Cerundolo, Vincenzo, Cerottini, Jean-Charles, Romero, Pedro
Format: Online
Language:English
Published: The Rockefeller University Press 1999
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195613/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195613/

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