Myricetin-Mediated Lifespan Extension in Caenorhabditis elegans Is Modulated by DAF-16

Myricetin-Mediated Lifespan Extension in Caenorhabditis elegans Is Modulated by DAF-16

Myricetin is a naturally occurring flavonol found in many plant based food sources. It increases the lifespan of Caenorhabditis elegans, but the molecular mechanisms are not yet fully understood. We have investigated the impact of this flavonoid on the transcription factors DAF-16 (C. elegans FoxO h...

Full description

Bibliographic Details
Main Authors:	Büchter, Christian, Ackermann, Daniela, Havermann, Susannah, Honnen, Sebastian, Chovolou, Yvonni, Fritz, Gerhard, Kampkötter, Andreas, Wätjen, Wim
Format:	Online
Language:	English
Published:	Molecular Diversity Preservation International (MDPI) 2013
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3709762/

Similar Items

Caffeic Acid Phenethylester Increases Stress Resistance and Enhances Lifespan in Caenorhabditis elegans by Modulation of the Insulin-Like DAF-16 Signalling Pathway
by: Havermann, Susannah, et al.
Published: (2014)

TSG (2,3,5,4′-Tetrahydroxystilbene-2-O-β-D-glucoside) from the Chinese Herb Polygonum multiflorum Increases Life Span and Stress Resistance of Caenorhabditis elegans
by: Büchter, Christian, et al.
Published: (2015)

Caenorhabditis elegans as Model System in Pharmacology and Toxicology: Effects of Flavonoids on Redox-Sensitive Signalling Pathways and Ageing
by: Koch, Karoline, et al.
Published: (2014)

Transcriptional regulation of Caenorhabditis elegans FOXO/DAF-16 modulates lifespan
by: Bansal, Ankita, et al.
Published: (2014)

Towards understanding the lifespan extension by reduced insulin signaling: bioinformatics analysis of DAF-16/FOXO direct targets in Caenorhabditis elegans
by: Li, Yan-Hui, et al.
Published: (2016)

A pharmacological network for lifespan extension in Caenorhabditis elegans
by: Ye, Xiaolan, et al.
Published: (2014)

CAMKII and Calcineurin regulate the lifespan of Caenorhabditis elegans through the FOXO transcription factor DAF-16
by: Tao, Li, et al.
Published: (2013)

Effects of Caenorhabditis elegans sgk-1 mutations on lifespan, stress resistance, and DAF-16/FoxO regulation
by: Chen, Albert Tzong-Yang, et al.
Published: (2013)

Rifampicin reduces advanced glycation end products and activates DAF-16 to increase lifespan in Caenorhabditis elegans
by: Golegaonkar, Sandeep, et al.
Published: (2015)

Catalpol Modulates Lifespan via DAF-16/FOXO and SKN-1/Nrf2 Activation in Caenorhabditis elegans
by: Seo, Hyun Won, et al.
Published: (2015)

Cell-Nonautonomous Signaling of FOXO/DAF-16 to the Stem Cells of Caenorhabditis elegans
by: Qi, Wenjing, et al.
Published: (2012)

Sterol-Derived Hormone(s) Controls Entry into Diapause in Caenorhabditis elegans by Consecutive Activation of DAF-12 and DAF-16
by: Matyash, Vitali, et al.
Published: (2004)

Studies of Caenorhabditis elegans DAF-2/insulin signaling reveal targets for pharmacological manipulation of lifespan
by: Gami, Minaxi S, et al.
Published: (2006)

daf-31 Encodes the Catalytic Subunit of N Alpha-Acetyltransferase that Regulates Caenorhabditis elegans Development, Metabolism and Adult Lifespan
by: Chen, Di, et al.
Published: (2014)

Elucidating the Mechanism of Weissella-dependent Lifespan Extension in Caenorhabditis elegans
by: Lee, Jiyun, et al.
Published: (2015)

Lifespan Extension Induced by Caffeine in Caenorhabditis elegans is Partially Dependent on Adenosine Signaling
by: Bridi, Jessika Cristina, et al.
Published: (2015)

Mechanisms of amino acid-mediated lifespan extension in Caenorhabditis elegans
by: Edwards, Clare, et al.
Published: (2015)

C. elegans VANG-1 Modulates Life Span via Insulin/IGF-1-Like Signaling
by: Honnen, Sebastian J., et al.
Published: (2012)

Blueberry polyphenols increase lifespan and thermotolerance in Caenorhabditis elegans
by: Wilson, Mark A, et al.
Published: (2006)

Variable Pathogenicity Determines Individual Lifespan in Caenorhabditis elegans
by: Sánchez-Blanco, Adolfo, et al.
Published: (2011)

l-Theanine extends lifespan of adult Caenorhabditis elegans
by: Zarse, Kim, et al.
Published: (2012)

Malate and Fumarate Extend Lifespan in Caenorhabditis elegans
by: Edwards, Clare B., et al.
Published: (2013)

The Lifespan-Promoting Effect of Otophylloside B in Caenorhabditis elegans
by: Yang, Jie, et al.
Published: (2015)

PCH-2 regulates Caenorhabditis elegans lifespan
by: Qian, Hong, et al.
Published: (2015)

Pharmacological classes that extend lifespan of Caenorhabditis elegans
by: Carretero, Maria, et al.
Published: (2015)

Bmk-1 regulates lifespan in Caenorhabditis elegans by activating hsp-16
by: Qian, Hong, et al.
Published: (2015)

Monascus-Fermented Dioscorea Enhances Oxidative Stress Resistance via DAF-16/FOXO in Caenorhabditis elegans
by: Shi, Yeu-Ching, et al.
Published: (2012)

DAF-16 and Δ9 Desaturase Genes Promote Cold Tolerance in Long-Lived Caenorhabditis elegans age-1 Mutants
by: Savory, Fiona R., et al.
Published: (2011)

ins-7 Gene Expression Is Partially Regulated by the DAF-16/IIS Signaling Pathway in Caenorhabditis elegans under Celecoxib Intervention
by: Zheng, Shanqing, et al.
Published: (2014)

Longevity Genes Revealed by Integrative Analysis of Isoform-Specific daf-16/FoxO Mutants of Caenorhabditis elegans
by: Chen, Albert Tzong-Yang, et al.
Published: (2015)

A Transcription Elongation Factor That Links Signals from the Reproductive System to Lifespan Extension in Caenorhabditis elegans
by: Ghazi, Arjumand, et al.
Published: (2009)

Extension of lifespan and protection against oxidative stress by an antioxidant herb mixture complex (KPG-7) in Caenorhabditis elegans
by: Moriwaki, Takahito, et al.
Published: (2013)

Lifespan extension and increased resistance to environmental stressors by N-Acetyl-L-Cysteine in Caenorhabditis elegans
by: Oh, Seung-Il, et al.
Published: (2015)

Acanthopanax sessiliflorus stem confers increased resistance to environmental stresses and lifespan extension in Caenorhabditis elegans
by: Park, Jin-Kook, et al.
Published: (2014)

LC–MS Proteomics Analysis of the Insulin/IGF-1-Deficient Caenorhabditis elegans daf-2(e1370) Mutant Reveals Extensive Restructuring of Intermediary Metabolism
by: Depuydt, Geert, et al.
Published: (2014)

Reduction of Mitoferrin Results in Abnormal Development and Extended Lifespan in Caenorhabditis elegans
by: Ren, Yaguang, et al.
Published: (2012)

Control of intestinal bacterial proliferation in regulation of lifespan in Caenorhabditis elegans
by: Portal-Celhay, Cynthia, et al.
Published: (2012)

Folate status of gut microbiome affects Caenorhabditis elegans lifespan
by: Nguyen, Theresa PT, et al.
Published: (2012)

Loss of NDG-4 extends lifespan and stress resistance in Caenorhabditis elegans
by: Brejning, Jeanette, et al.
Published: (2014)

Fish oil changes the lifespan of Caenorhabditis elegans via lipid peroxidation
by: Sugawara, Soko, et al.
Published: (2013)