Studies of Caenorhabditis elegans DAF-2/insulin signaling reveal targets for pharmacological manipulation of lifespan
Much excitement has arisen from the observation that decrements in insulin-like signaling can dramatically extend lifespan in the nematode, Caenorhabditis elegans, and fruitfly, Drosophila melanogaster. In addition, there are tantalizing hints that the IGF-I pathway in mice may have similar effects....
| Main Authors: | , |
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| Format: | Online |
| Language: | English |
| Published: |
Blackwell Publishing Ltd
2006
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1413578/ |