Rifampicin reduces advanced glycation end products and activates DAF-16 to increase lifespan in Caenorhabditis elegans
Advanced glycation end products (AGEs) are formed when glucose reacts nonenzymatically with proteins; these modifications are implicated in aging and pathogenesis of many age-related diseases including type II diabetes, atherosclerosis, and neurodegenerative disorders. Thus, pharmaceutical intervent...
Main Authors: | , , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
BlackWell Publishing Ltd
2015
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4406675/ |