Deletion of immunomodulator C6 from vaccinia virus strain Western Reserve enhances virus immunogenicity and vaccine efficacy
Vectors based on vaccinia virus (VACV), the vaccine used to eradicate smallpox, are currently popular candidates for the vaccination against numerous infectious diseases including malaria and AIDS. Although VACV induces robust cellular and humoral responses, enhancing the safety and efficacy of thes...
Main Authors: | Sumner, Rebecca P., Ren, Hongwei, Smith, Geoffrey L. |
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Format: | Online |
Language: | English |
Published: |
Society for General Microbiology
2013
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3709586/ |
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