Deletion of immunomodulator C6 from vaccinia virus strain Western Reserve enhances virus immunogenicity and vaccine efficacy

by Sumner, Rebecca P., Ren, Hongwei, Smith, Geoffrey L.
Published 2013

Vaccinia virus protein C4 inhibits NF-κB activation and promotes virus virulence

by Ember, Stuart W. J., Ren, Hongwei, Ferguson, Brian J., Smith, Geoffrey L.
Published 2012

DNA-PK is a DNA sensor for IRF-3-dependent innate immunity

by Ferguson, Brian J, Mansur, Daniel S, Peters, Nicholas E, Ren, Hongwei, Smith, Geoffrey L
Published 2012

Vaccinia virus protein K7 is a virulence factor that alters the acute immune response to infection

by Benfield, Camilla T. O., Ren, Hongwei, Lucas, Stuart J., Bahsoun, Basma, Smith, Geoffrey L.
Published 2013

Increased attenuation but decreased immunogenicity by deletion of multiple vaccinia virus immunomodulators

by Sumner, Rebecca P., Ren, Hongwei, Ferguson, Brian J., Smith, Geoffrey L.
Published 2016

Inhibition of Translation Initiation by Protein 169: A Vaccinia Virus Strategy to Suppress Innate and Adaptive Immunity and Alter Virus Virulence

by Strnadova, Pavla, Ren, Hongwei, Valentine, Robert, Mazzon, Michela, Sweeney, Trevor R., Brierley, Ian, Smith, Geoffrey L.
Published 2015

Enhancement of CD8+ T-cell memory by removal of a vaccinia virus nuclear factor-κB inhibitor

by Ren, Hongwei, Ferguson, Brian J, de Motes, Carlos Maluquer, Sumner, Rebecca P, Harman, Laura E R, Smith, Geoffrey L
Published 2015

Vaccinia Virus Protein C6 Is a Virulence Factor that Binds TBK-1 Adaptor Proteins and Inhibits Activation of IRF3 and IRF7

by Unterholzner, Leonie, Sumner, Rebecca P., Baran, Marcin, Ren, Hongwei, Mansur, Daniel S., Bourke, Nollaig M., Randow, Felix, Smith, Geoffrey L., Bowie, Andrew G.
Published 2011

Vaccinia virus protein N2 is a nuclear IRF3 inhibitor that promotes virulence

by Ferguson, Brian J., Benfield, Camilla T. O., Ren, Hongwei, Lee, Vivian H., Frazer, Gordon L., Strnadova, Pavla, Sumner, Rebecca P., Smith, Geoffrey L.
Published 2013

Poxvirus Targeting of E3 Ligase β-TrCP by Molecular Mimicry: A Mechanism to Inhibit NF-κB Activation and Promote Immune Evasion and Virulence

by Mansur, Daniel S., Maluquer de Motes, Carlos, Unterholzner, Leonie, Sumner, Rebecca P., Ferguson, Brian J., Ren, Hongwei, Strnadova, Pavla, Bowie, Andrew G., Smith, Geoffrey L.
Published 2013

A Mechanism for the Inhibition of DNA-PK-Mediated DNA Sensing by a Virus

by Peters, Nicholas E., Ferguson, Brian J., Mazzon, Michela, Fahy, Aodhnait S., Krysztofinska, Ewelina, Arribas-Bosacoma, Raquel, Pearl, Laurence H., Ren, Hongwei, Smith, Geoffrey L.
Published 2013

Inhibition of Apoptosis and NF-κB Activation by Vaccinia Protein N1 Occur via Distinct Binding Surfaces and Make Different Contributions to Virulence

by Maluquer de Motes, Carlos, Cooray, Samantha, Ren, Hongwei, Almeida, Gabriel M. F., McGourty, Kieran, Bahar, Mohammad W., Stuart, David I., Grimes, Jonathan M., Graham, Stephen C., Smith, Geoffrey L.
Published 2011

­­LUBAC deficiency perturbs TLR3 signaling to cause immunodeficiency and autoinflammation

by Zinngrebe, Julia, Rieser, Eva, Taraborrelli, Lucia, Peltzer, Nieves, Hartwig, Torsten, Ren, Hongwei, Kovács, Ildikó, Endres, Cornelia, Draber, Peter, Darding, Maurice, von Karstedt, Silvia, Lemke, Johannes, Dome, Balazs, Bergmann, Michael, Ferguson, Brian J., Walczak, Henning
Published 2016