Zscan4 restores the developmental potency of embryonic stem cells

Zscan4 restores the developmental potency of embryonic stem cells

The developmental potency of mouse embryonic stem (ES) cells, which is the ability to contribute to a whole embryo is known to deteriorate during long-term cell culture. Previously we have shown that ES cells oscillate between Zscan4- and Zscan4+ states, and the transient activation of Zscan4 is req...

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Bibliographic Details
Main Authors: Amano, Tomokazu, Hirata, Tetsuya, Falco, Geppino, Monti, Manuela, Sharova, Lioudmila V., Amano, Misa, Sheer, Sarah, Hoang, Hien G., Piao, Yulan, Stagg, Carole A., Yamamizu, Kohei, Akiyama, Tomohiko, Ko, Minoru S.H.
Format: Online
Language:English
Published: 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3682791/

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