Telomeres, A Busy Platform for Cell Signaling

Telomeres are the terminal structures at the ends of linear chromosomes that represent a solution to the end replication problem. Specific binding of the six-protein subunit complex shelterin to telomeric, repetitive TTAGGG DNA sequences contributes to the stable architecture and maintenance of telo...

Full description

Bibliographic Details
Main Authors: Gardano, Laura, Pucci, Fabio, Christian, Larissa, Le Bihan, Thierry, Harrington, Lea
Format: Online
Language:English
Published: Frontiers Media S.A. 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3677152/