Enforced telomere elongation increases the sensitivity of human tumour cells to ionizing radiation
•Telomere elongation decreases human tumour cell viability after irradiation.•The longer the telomeres, the greater the sensitivity to sub-lethal irradiation.•Increased sensitivity to irradiation is independent of telomere signal-free ends.
Main Authors: | , |
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Format: | Online |
Language: | English |
Published: |
Elsevier
2015
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4286114/ |