A powerful and efficient set test for genetic markers that handles confounders
Motivation: Approaches for testing sets of variants, such as a set of rare or common variants within a gene or pathway, for association with complex traits are important. In particular, set tests allow for aggregation of weak signal within a set, can capture interplay among variants and reduce the b...
Main Authors: | Listgarten, Jennifer, Lippert, Christoph, Kang, Eun Yong, Xiang, Jing, Kadie, Carl M., Heckerman, David |
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Format: | Online |
Language: | English |
Published: |
Oxford University Press
2013
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3673214/ |
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