Leveraging Hierarchical Population Structure in Discrete Association Studies

Population structure can confound the identification of correlations in biological data. Such confounding has been recognized in multiple biological disciplines, resulting in a disparate collection of proposed solutions. We examine several methods that correct for confounding on discrete data with h...

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Bibliographic Details
Main Authors: Carlson, Jonathan, Kadie, Carl, Mallal, Simon, Heckerman, David
Format: Online
Language:English
Published: Public Library of Science 2007
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1899226/