A Statistical Framework for Modeling HLA-Dependent T Cell Response Data

The identification of T cell epitopes and their HLA (human leukocyte antigen) restrictions is important for applications such as the design of cellular vaccines for HIV. Traditional methods for such identification are costly and time-consuming. Recently, a more expeditious laboratory technique using...

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Bibliographic Details
Main Authors: Listgarten, Jennifer, Frahm, Nicole, Kadie, Carl, Brander, Christian, Heckerman, David
Format: Online
Language:English
Published: Public Library of Science 2007
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2014793/