Clinical Grade Purification and Expansion of NK Cell Products for an Optimized Manufacturing Protocol

Clinical Grade Purification and Expansion of NK Cell Products for an Optimized Manufacturing Protocol

Allogeneic natural killer (NK) cells are used for adoptive immunotherapy after stem cell transplantation. In order to overcome technical limitations in NK cell purification and activation, the following study investigates the impact of different variables on NK cell recovery, cytotoxicity, and T-cel...

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Bibliographic Details
Main Authors: Koehl, Ulrike, Brehm, Claudia, Huenecke, Sabine, Zimmermann, Stefanie-Yvonne, Kloess, Stephan, Bremm, Melanie, Ullrich, Evelyn, Soerensen, Jan, Quaiser, Andrea, Erben, Stephanie, Wunram, Claudia, Gardlowski, Tanja, Auth, Eileen, Tonn, Torsten, Seidl, Christian, Meyer-Monard, Sandrine, Stern, Martin, Passweg, Jakob, Klingebiel, Thomas, Bader, Peter, Schwabe, Dirk, Esser, Ruth
Format: Online
Language:English
Published: Frontiers Media S.A. 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3656406/

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