Cetuximab Reconstitutes Pro-Inflammatory Cytokine Secretions and Tumor-Infiltrating Capabilities of sMICA-Inhibited NK Cells in HNSCC Tumor Spheroids
Immunosuppressive factors, such as soluble major histocompatibility complex class I chain-related peptide A (sMICA) and transforming growth factor beta 1 (TGF-β1), are involved in tumor immune escape mechanisms (TIEMs) exhibited by head and neck squamous cell carcinomas (HNSCCs) and may represent op...
Main Authors: | , , , , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
Frontiers Media S.A.
2015
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4629470/ |