Selection and expansion of natural killer cells for NK cell-based immunotherapy

Natural killer (NK) cells have been used in several clinical trials as adaptive immunotherapy. The low numbers of these cells in peripheral blood mononuclear cells (PBMC) have resulted in various approaches to preferentially expand primary NK cells from PBMC. While some clinical trials have used th...

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Bibliographic Details
Main Authors: Becker, Petra S. A., Suck, Garnet, Nowakowska, Paulina, Ullrich, Evelyn, Seifried, Erhard, Bader, Peter, Tonn, Torsten, Seidl, Christian
Format: Online
Language:English
Published: Springer Berlin Heidelberg 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826432/