Pre-immunization with an Intramuscular Injection of AAV9-Human Erythropoietin Vectors Reduces the Vector-Mediated Transduction following Re-Administration in Rat Brain

Pre-immunization with an Intramuscular Injection of AAV9-Human Erythropoietin Vectors Reduces the Vector-Mediated Transduction following Re-Administration in Rat Brain

We have recently demonstrated that adeno-associated virus serotype 9 (AAV9)-mediated human erythropoietin (hEPO) gene delivery into the brain protects dopaminergic (DA) neurons in the substantia nigra in a rat model of Parkinson's disease. In the present study, we examined whether pre-exposure...

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Bibliographic Details
Main Authors: Yang, Chun, Yang, Wei-Hua, Chen, Sha-Sha, Ma, Bao-Feng, Li, Bin, Lu, Tao, Qu, Ting-Yu, Klein, Ronald L., Zhao, Li-Ru, Duan, Wei-Ming
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3648480/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3648480/

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