Innate Immune Responses to AAV Vectors

Gene replacement therapy by in vivo delivery of adeno-associated virus (AAV) is attractive as a potential treatment for a variety of genetic disorders. However, while AAV has been used successfully in many models, other experiments in clinical trials and in animal models have been hampered by undesi...

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Bibliographic Details
Main Authors: Rogers, Geoffrey L., Martino, Ashley T., Aslanidi, George V., Jayandharan, Giridhara R., Srivastava, Arun, Herzog, Roland W.
Format: Online
Language:English
Published: Frontiers Research Foundation 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3175613/